First Report of an Enterobacter ludwigii Isolate Coharboring NDM-1 and OXA-48 Carbapenemases

The First Klebsiella pneumoniae Isolate Co-Producing OXA-48 and NDM-1 in Turkey

Dear Editor Resistance to broad-spectrum antimicrobials is a well-known challenge in treating Enterobacteriaceae infection worldwide. Carbapenems are an important class of antimicrobials used in treatment against these organisms, although increasing resistance to carbapenems has been reported among Enterobacteriaceae [1]. The production of OXA-48 was first described in Klebsiella pneumoniae iso...

A silent outbreak due to Klebsiella pneumoniae that co-produced NDM-1 and OXA-48 carbapenemases, and infection control measures

Objective(s): Infections due to carbapenemase-producing Klebsiella pneumoniae are associated with high morbidity and mortality. In this study, we report a hospital outbreak due to co-producing OXA-48 and NDM-1 K. pneumoniae clone. The aim of the study is to investigate the clonal relationship of strains, risk factors of outbreak and infection control measures.<em...

First report of OXA-181 and NDM-1 from a clinical Klebsiella pneumoniae isolate from Nigeria.

OXA-48-like carbapenemases: the phantom menace.

OXA-48-type carbapenem-hydrolysing class D β-lactamases are increasingly reported in enterobacterial species. To date, six OXA-48-like variants have been identified, with OXA-48 being the most widespread. They differ by a few amino acid substitutions or deletions (one to five amino acids). The enzymes hydrolyse penicillins at a high level and carbapenems at a low level, sparing broad-spectrum c...

Complete Genome Sequence of Enterobacter cloacae 704SK10, an OXA-48-Encoding Wastewater Isolate

Here we present the complete genome sequence of Enterobacter cloacae 704SK10, a Swiss wastewater isolate encoding an OXA-48 carbapenemase. Assembly resulted in closed sequences of the 4,876,946-bp chromosome, a 111,184-bp IncF plasmid, and an OXA-48-encoding IncL plasmid (63,458 bp) nearly identical to the previously described plasmid pOXA-48.